Fortune 500 Pharma Company
the eTMF application to
The growth of clinical trials in terms of scope and complexity is transforming the approach to content management in pharmaceutical, as well as biotechnology companies. Electronic Trial Master Files (TMFs) are, therefore, the go-to place for maintaining a central repository for the storage of clinical trial documents for use in regulatory submissions. With the next generation of eTMFs, more advanced technologies and capabilities will be rendered for sure.
Our client is a research-based
global biopharmaceutical company headquartered in the USA. With an innovative approach
and global resources, this company is engaged in the discovery, development, and
manufacturing of healthcare products
and vaccines. This involves extensive research, documentation, creation of case studies, and
compilation of data in the
form of images, documents, and other digital content management.
Our client uses eTMF – electronic trial master file for building these documentations for clinical trials. Celestial has been instrumental in the eTMF Next-gen project for our client, i.e., upgrading this eTMF application to use the latest production version of Ext JS 7.2.
Revamp the UI of the application
Upgrade the frontend to the latest version of Sencha Ext JS
Re-architecting the application to a modern framework
The eTMF Next-gen project’s objective was to upgrade the eTMF application to use the latest production version of Ext JS 7.x and to re-architect the application so that it uses the inherent automated functions and features such Sencha CMD, MVVM, as well as proper theming. The existing eTMF application lacked the “Next Generation” TMF capabilities like automated quality checks, proactive monitoring, modeling, and predicting all aspects of records management from the study, design through closeout. We assisted in upgrading the older Ext JS version to the latest which follows the inherent automated functions and features such as Sencha CMD and MVVM.
4.2 to 7.2 version
The eTMF application was upgraded to the latest version of Ext JS with improvements in grid features, data binding, and even faster loading time.
Re-architected the application to Model-view-viewmodel which resulted in a UI-based design system with improved application productivity, maintainability, flexibility, testability, and reusability.
The new app offered advanced functionalities such as automated quality checks, eliminating the need for manual QC findings, and providing alerts for low-performing studies and sites.
We used Model-view-viewmodel (MVVM) architecture for
this eTMF Next gen project. The best part of
MVVM architecture is
that we can attach multiple views to a single viewmodel.
- Frontend upgraded to latest version of Ext JS
- Brought the application to MVVM architecture
- 85% Performance improvement
- 80% faster loading time